Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors-Reference-Cited by-同舟云学术

Exploring the Chemistry of Alkaloids from Malaysian Mitragyna speciosa (Kratom) and the Role of Oxindoles on Human Opioid Receptors

Published:2021-02-26 Issue:4 Volume:84 Page:1034-1043
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Chear Nelson Jeng-Yeou¹²,León Francisco²^ORCID,Sharma Abhisheak³⁴^ORCID,Kanumuri Siva Rama Raju³⁴,Zwolinski Grant²,Abboud Khalil A.⁵,Singh Darshan¹,Restrepo Luis F.⁶,Patel Avi⁶,Hiranita Takato⁶,Ramanathan Surash¹,Hampson Aidan J.⁷,McMahon Lance R.⁶,McCurdy Christopher R.²³⁴^ORCID

Affiliation:

1. Centre for Drug Research, Universiti Sains Malaysia, 11800 Minden, Penang, Malaysia

2. Department of Medicinal Chemistry, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

3. Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

4. Translational Drug Development Core, Clinical and Translational Sciences Institute, University of Florida, Gainesville, Florida 32610, United States

5. Department of Chemistry, University of Florida, Gainesville, Florida 32611, United States

6. Department of Pharmacodynamics, College of Pharmacy, University of Florida, Gainesville, Florida 32610, United States

7. Division of Therapeutics and Medical Consequences, National Institute on Drug Abuse, National Institutes of Health, Bethesda, Maryland 20892, United States

Funder

National Center for Advancing Translational Sciences

Universiti Sains Malaysia

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.0c01055

Reference28 articles.

1. Changing trends in the use of kratom (Mitragyna speciosa) in Southeast Asia

2. Gogineni, V.; León, F.; Avery, B. A.; McCurdy, C. R.; Cutler, S. J. In Kratom and other Mitragynines: The Chemistry and Pharmacology of Opioids from Non-opium Source; Raffa, R., Ed. CRC Press: New York, 2014; pp 77–94.

3. Phytochemical Characterization of the Leaves of Mitragyna Speciosa Grown in USA

4. Simultaneous quantification of ten key Kratom alkaloids in Mitragyna speciosa leaf extracts and commercial products by ultra‐performance liquid chromatography−tandem mass spectrometry

5. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects

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