Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products-Reference-Cited by-同舟云学术

Discovery of Dual Inhibitors for Wild Type and D816V Mutant of c-KIT Kinase through Virtual and Biochemical Screening of Natural Products

Published:2016-01-25 Issue:2 Volume:79 Page:293-299
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Park Hwangseo¹,Lee Soyoung²,Hong Sungwoo²

Affiliation:

1. Department of Bioscience and Biotechnology & Institute of Anticancer Medicine Development, Sejong University, 209 Neungdong-ro, Kwangjin-gu, Seoul 143-747, Korea

2. Center for Catalytic Hydrocarbon Functionalizations, Institute for Basic Science (IBS) & Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Korea

Funder

Ministry of Science, ICT and Future Planning

Institute for Basic Science

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.5b00851

Reference46 articles.

1. Structure and regulation of Kit protein-tyrosine kinase—The stem cell factor receptor

2. Protein kinases and phosphatases: The Yin and Yang of protein phosphorylation and signaling