Heterologous Expression of the Formicamycin Biosynthetic Gene Cluster Unveils Glycosylated Fasamycin Congeners-Reference-Cited by-同舟云学术

Heterologous Expression of the Formicamycin Biosynthetic Gene Cluster Unveils Glycosylated Fasamycin Congeners

Published:2023-06-16 Issue:7 Volume:86 Page:1677-1689
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

McDonald Hannah P.¹^ORCID,Alford Abigail¹^ORCID,Devine Rebecca¹^ORCID,Hems Edward S.¹,Nepogodiev Sergey A.²^ORCID,Arnold Corinne J.¹^ORCID,Rejzek Martin³^ORCID,Stanley-Smith Anna⁴,Holmes Neil A.¹^ORCID,Hutchings Matthew I.¹^ORCID,Wilkinson Barrie¹^ORCID

Affiliation:

1. Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, U.K.

2. NMR Platform, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.

3. Chemistry Platform, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.

4. Isomerase, Chesterford Research Park, Cambridge CB10 1XL, U.K.

Funder

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.3c00052

Reference25 articles.

1. Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants

2. Complete genome sequence of Streptomyces formicae KY5, the formicamycin producer

3. Environmental DNA-Encoded Antibiotics Fasamycins A and B Inhibit FabF in Type II Fatty Acid Biosynthesis

4. Streptovertimycins A–H, new fasamycin-type antibiotics produced by a soil-derived Streptomyces morookaense strain

5. Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. I. The taxonomy of the producing strain, and the fermentation, isolation and antibacterial activities

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