Metabolomic Analysis and Antiviral Screening of a Marine Algae Library Yield Jobosic Acid (2,5-Dimethyltetradecanoic Acid) as a Selective Inhibitor of SARS-CoV-2

Author:

Matos-Hernández Marie L.1ORCID,Samples Robert2ORCID,Dyer Grayce1ORCID,Casimir Montán Victoria M.3ORCID,Morales-Colón Chris A.3ORCID,Salvino Joseph M.4ORCID,Montaner Luis J.4,Cassel Joel A.4,Messick Troy E.4,Tietjen Ian4,Caro-Diaz Eduardo J. E.1ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, School of Pharmacy, University of Puerto Rico−Medical Sciences Campus, San Juan, Puerto Rico 00935, United States

2. Center for Mass Spectrometry, Smith College, Northampton, Massachusetts 01063, United States

3. Department of Chemistry, Natural Sciences College, University of Puerto Rico−Rio Piedras Campus, San Juan, Puerto Rico 00925, United States

4. The Wistar Institute, Philadelphia, Pennsylvania 19104, United States

Funder

Canadian Institutes of Health Research

Commonwealth of Pennsylvania

American Society of Pharmacognosy

Puerto Rico Sea Grant College, University of Puerto Rico

Philadelphia Foundation

National Institute on Minority Health and Health Disparities

National Institute of General Medical Sciences

Herbert Kean, M.D., Family Professorship

Publisher

American Chemical Society (ACS)

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