Cannabidiol Protects Human Skin Keratinocytes from Hydrogen-Peroxide-Induced Oxidative Stress via Modulation of the Caspase-1

Cannabidiol Protects Human Skin Keratinocytes from Hydrogen-Peroxide-Induced Oxidative Stress via Modulation of the Caspase-1–IL-1β Axis

Published:2021-05-06 Issue:5 Volume:84 Page:1563-1572
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Liu Chang¹,Li Huifang¹,Xu Feng²,Jiang Xian³,Ma Hang¹^ORCID,Seeram Navindra P.¹^ORCID

Affiliation:

1. Bioactive Botanical Research Laboratory, Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island 02881, United States

2. College of Pharmacy, Guizhou University of Traditional Chinese Medicine, Guiyang 550001, China

3. Department of Dermatology, Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology (CIII), Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.1c00083

Reference43 articles.

1. Cannabidiol: An Overview of Some Pharmacological Aspects

2. Anti-inflammatory and antioxidant effects of a combination of cannabidiol and moringin in LPS-stimulated macrophages

3. Antioxidative and Anti-Inflammatory Properties of Cannabidiol

4. Cannabidiol protects keratinocyte cell membranes following exposure to UVB and hydrogen peroxide

5. Cannabidiol Regulates the Expression of Keratinocyte Proteins Involved in the Inflammation Process through Transcriptional Regulation

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