Thiazolidinedione-Based Structure Modification of Celastrol Provides Thiazolidinedione-Conjugated Derivatives as Potent Agents against Non-Small-Cell Lung Cancer Cells through a Mitochondria-Mediated Apoptotic Pathway-Reference-Cited by-同舟云学术

Thiazolidinedione-Based Structure Modification of Celastrol Provides Thiazolidinedione-Conjugated Derivatives as Potent Agents against Non-Small-Cell Lung Cancer Cells through a Mitochondria-Mediated Apoptotic Pathway

Published:2022-03-08 Issue:4 Volume:85 Page:1147-1156
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Fu Xuefeng¹,Mao Qing¹,Zhang Bing¹,Lv Jialun¹,Ping Kunqi¹,Zhang Peng¹,Lin Fengwei¹,Zhao Jiaxing¹,Feng Yao¹²,Yang Jincheng²,Wang Huiyu²,Zhang Lei³,Mou Yanhua⁴,Wang Shaojie¹^ORCID

Affiliation:

1. Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, 103 Culture Road, Shenhe District, Shenyang 110016, China

2. Ningxia Kangya Pharmaceutical Co., Ltd., Yinchuan 750000, China

3. Department of Neurosurgery, Shengjing Hospital of China Medical University, Shenyang 110016, China

4. Department of Pharmacology, Shenyang Pharmaceutical University, 103 Culture Road, Shenhe District, Shenyang 110016, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.2c00104

Reference48 articles.

1. Establishment of adventitious root cultures from leaf explants of Tripterygium wilfordii (thunder god vine) for the production of celastrol

2. Celastrol: Progresses in structure-modifications, structure-activity relationships, pharmacology and toxicology