Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor-1 and Cyclotide Kalata B1-Reference-Cited by-同舟云学术

Exploring the Limits of Cyanobactin Macrocyclase PatGmac: Cyclization of PawS-Derived Peptide Sunflower Trypsin Inhibitor-1 and Cyclotide Kalata B1

Published:2023-03-14 Issue:3 Volume:86 Page:566-573
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Muhammad Taj¹,Houssen Wael E²³^ORCID,Thomas Louise²³,Alexandru-Crivac Cristina-Nicoleta²³,Gunasekera Sunithi¹^ORCID,Jaspars Marcel²,Göransson Ulf¹^ORCID

Affiliation:

1. Pharmacognosy, Department of Pharmaceutical Biosciences, Uppsala University, Biomedical Centre, Box 591, SE-75124 Uppsala, Sweden

2. Department of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen AB24 3UE, Scotland, U.K.

3. Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, Scotland, U.K.

Funder

Engineering and Physical Sciences Research Council

Vetenskapsrådet

Carl Tryggers Stiftelse för Vetenskaplig Forskning

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jnatprod.2c01158

Reference47 articles.

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3. Buried treasure: biosynthesis, structures and applications of cyclic peptides hidden in seed storage albumins

4. The mechanism of patellamide macrocyclization revealed by the characterization of the PatG macrocyclase domain

5. Cyclotides as drug design scaffolds