Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme

Author:

Avalon Nicole E.1ORCID,Nafie Jordan2,De Marco Verissimo Carolina3,Warrensford Luke C.1ORCID,Dietrick Sarah G.1,Pittman Amanda R.1,Young Ryan M.4,Kearns Fiona L.1,Smalley Tracess5,Binning Jennifer M.5,Dalton John P.3,Johnson Mark P.4,Woodcock H. Lee1ORCID,Allcock A. Louise4ORCID,Baker Bill J.1

Affiliation:

1. Department of Chemistry, University of South Florida, Tampa, Florida 33620, United States

2. BioTools, Inc., Jupiter, Florida 33458, United States

3. Molecular Parasitology Laboratory (MPL), Centre for One Health and Ryan Institute, School of Natural Science, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland

4. School of Natural Sciences and Ryan Institute, National University of Ireland Galway, H91 TK33 Galway, Republic of Ireland

5. Department of Molecular Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida 33612, United States

Funder

Science Foundation Ireland

European Regional Development Fund

National Institutes of Health

NMBLI

Science Foundation Ireland and the Marine Institute

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

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