Conformationally Constrained Anesthetic Steroids That Modulate GABAA Receptors-Reference-Cited by-同舟云学术

Conformationally Constrained Anesthetic Steroids That Modulate GABAA Receptors

Published:2000-10-19 Issue:22 Volume:43 Page:4118-4125
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Anderson Alison¹,Boyd Andrew C.¹,Clark John K.¹,Fielding Lee¹,Gemmell David K.¹,Hamilton Niall M.¹,Maidment Maurice S.¹,May Valerie¹,McGuire Ross¹,McPhail Petula¹,Sansbury Francis H.¹,Sundaram Hardy¹,Taylor Robert¹

Affiliation:

1. Research and Development, Organon Laboratories Ltd., Newhouse, Motherwell, Lanarkshire ML1 5SH, Scotland, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000977e

Reference55 articles.

1. Steroid Hormone Metabolites Are Barbiturate-Like Modulators of the GABA Receptor

2. Neurosteroids: Endogenous bimodal modulators of the GABAA receptor mechanism of action and physiological significance

3. Neurosteroids and GABAA receptor function

4. Anticonvulsant steroids and the GABA/benzodiazepine receptor-chloride ionophore complex

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