Role of P‐glycoprotein‐mediated secretion in absorptive drug permeabiity: An approach using passive membrane permeability and affinity to P‐glycoprotein††Dedicated to Prof. B. C. Lippold on the occasion of his 60th birthday.

Author:

Doppenschmitt Stephan,Spahn‐Langguth Hildegard,Regårdh Carl Gunnar,Langguth Peter

Publisher

American Geophysical Union (AGU)

Subject

Pharmaceutical Science

Reference17 articles.

1. P‐Glycoprotein transporters and the gastrointestinal tract: Evaluation of the potential in vivo relevance of in vitro data employing talinolol as model compound;Spahn‐Langguth;Int. J. Clin. Pharmacol. Ther.,1998

2. ATP‐Binding Cassette Proteins, Common Denominators between Ion Channels, Transporters, and Enzymes;Greenberger;Trends Cardiovasc. Med.,1994

3. Molecular aspects of hepatobiliary transport;Müller;Am. J. Physiol.,1997

4. Homologous disruption of the murine mdr2 P‐glycoprotein gene leads to a complete absence of phospholipid in the bile and liver desease;Smit;Cell,1993

5. Overlapping substrate specificities and tissues distribution of cytochrome P‐450 3A and P‐glycoprotein have implications for drug delivery and activity in cancer chemotherapy;Wacher;Mol. Carcinogen.,1995

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