Key Determinants in the Occurrence of Clonal Variation in Humanized Antibody Expression of CHO Cells during Dihydrofolate Reductase Mediated Gene Amplification-Reference-Cited by-同舟云学术

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Key Determinants in the Occurrence of Clonal Variation in Humanized Antibody Expression of CHO Cells during Dihydrofolate Reductase Mediated Gene Amplification

Published:2001-02-02 Issue:1 Volume:17 Page:69-75
ISSN:8756-7938
Container-title:Biotechnology Progress
language:en
Short-container-title:Biotechnol. Prog.

Author:

Kim N.S.,Byun T.H.,Lee G.M.

Publisher

Wiley

Subject

Biotechnology

Cited by 51 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genomic barcoding for clonal diversity monitoring and control in cell-based complex antibody production;Scientific Reports;2024-06-25

2. Comprehensive characterization of dihydrofolate reductase‐mediated gene amplification for the establishment of recombinant human embryonic kidney 293 cells producing monoclonal antibodies;Biotechnology Journal;2020-12-30

3. A Microfluidic Single-Cell Cloning (SCC) Device for the Generation of Monoclonal Cells;Cells;2020-06-18

4. Overexpression of the mitochondrial pyruvate carrier reduces lactate production and increases recombinant protein productivity in CHO cells;Biotechnology and Bioengineering;2020-06-17

5. Enhanced CHO Clone Screening: Application of Targeted Locus Amplification and Next‐Generation Sequencing Technologies for Cell Line Development;Biotechnology Journal;2019-05-15

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