Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of 2- and 3-Aminobenzo[b]thiophene Derivatives as Antimitotic Agents and Inhibitors of Tubulin Polymerization

Published:2007-04-10 Issue:9 Volume:50 Page:2273-2277
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Romagnoli Romeo¹,Baraldi Pier Giovanni¹,Carrion Maria Dora¹,Cara Carlota Lopez¹,Preti Delia¹,Fruttarolo Francesca¹,Pavani Maria Giovanna¹,Tabrizi Mojgan Aghazadeh¹,Tolomeo Manlio¹,Grimaudo Stefania¹,Di Cristina Antonella¹,Balzarini Jan¹,Hadfield John A.¹,Brancale Andrea¹,Hamel Ernest¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche, Università di Ferrara, 44100 Ferrara, Italy, Dipartimento di Oncologia, Divisione di Ematologia e Servizio AIDS, Policlinico “P. Giaccone”, Università di Palermo, Palermo, Italy, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Minderbroedersstraat 10, B-3000 Leuven, Belgium, Centre for Molecular Drug Design, Cockroft Building, University of Salford, Manchester M5 4W5, U.K., The Welsh School of Pharmacy, Cardiff University, King Edward...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070050f

Reference23 articles.

1. Review: Tubulin Function, Action of Antitubulin Drugs, and New Drug Development

2. Understanding microtubule dynamics for improved cancer therapy

3. Disrupting tumour blood vessels

4. Vascular-Targeted Therapies in Oncology

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