Synthesis and Structure−Activity Relationships of Chiral Allosteric Modifiers of Hemoglobin-Reference-Cited by-同舟云学术

Synthesis and Structure−Activity Relationships of Chiral Allosteric Modifiers of Hemoglobin

Published:2000-11-18 Issue:25 Volume:43 Page:4726-4737
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Phelps Grella Melissa¹,Danso-Danquah Richmond¹,Safo Martin K.¹,Joshi Gajanan S.¹,Kister Jean¹,Marden Michael¹,Hoffman Stephen J.¹,Abraham Donald J.¹

Affiliation:

1. Department of Medicinal Chemistry, School of Pharmacy, Institute for Structural Biology and Drug Discovery, Virginia Commonwealth University, Richmond, Virginia 23298-0133, Allos Therapeutics, Inc., 7000 North Broadway, Suite 400, Denver, Colorado 80221, and Physiologie et Physiopathologie Moleculaires, INSERM U 299, Du Globule Rouge, 78 Rue du General Leclerc, 94275 Le Kremlin Bicetre, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000199q

Reference32 articles.

1. Stereochemistry of Cooperative Effects in Haemoglobin: Haem–Haem Interaction and the Problem of Allostery

2. The Modification of Hemoglobin Affinity for Oxygen and Tumor Radiosensitivity by Antilipidemic Drugs

3. Physiological and x-ray studies of potential antisickling agents.

4. [(E)-1-[123I]Iodo-1-penten-5-yl]triphenylphosphonium iodide: convenient preparation of a potentially useful myocardial perfusion agent

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