Formal Syntheses of (±)-Platensimycin and (±)-Platencin via a Dual-Mode Lewis Acid Induced Cascade Cyclization Approach-Reference-Cited by-同舟云学术

Formal Syntheses of (±)-Platensimycin and (±)-Platencin via a Dual-Mode Lewis Acid Induced Cascade Cyclization Approach

Published:2013-08-05 Issue:16 Volume:78 Page:7912-7929
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Zhu Lizhi¹,Zhou Congshan¹²,Yang Wei¹,He Shuzhong¹,Cheng Gui-Juan¹,Zhang Xinhao¹,Lee Chi-Sing¹

Affiliation:

1. Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Peking University Shenzhen Graduate School, Shenzhen University Town, Xili, Shenzhen 518055, China

2. College of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang 414006, China

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo401105q

Reference126 articles.

1. Platensimycin is a selective FabF inhibitor with potent antibiotic properties

2. Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties

3. Biosynthetic Studies of Platensimycin

4. Dedicated ent-kaurene and ent-atiserene synthases for platensimycin and platencin biosynthesis

5. Platensimycin, a New Antibiotic and “Superbug Challenger” from Nature

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