Reaction of Human Cytochrome P450 3A4 with Peroxynitrite: Nitrotyrosine Formation on the Proximal Side Impairs Its Interaction with NADPH-Cytochrome P450 Reductase-Reference-Cited by-同舟云学术

Reaction of Human Cytochrome P450 3A4 with Peroxynitrite: Nitrotyrosine Formation on the Proximal Side Impairs Its Interaction with NADPH-Cytochrome P450 Reductase

Published:2012-10-16 Issue:12 Volume:25 Page:2642-2653
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Lin Hsia-lien¹,Kenaan Cesar¹,Zhang Haoming¹,Hollenberg Paul F.¹

Affiliation:

1. Department of Pharmacology, University of Michigan, 2301 MSRB III, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109-5632, United States

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx3002753

Reference38 articles.

1. Biological Tyrosine Nitration: A Pathophysiological Function of Nitric Oxide and Reactive Oxygen Species

2. Unraveling peroxynitrite formation in biological systems

3. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly

4. Superoxide Dismutase Catalyzes Nitration of Tyrosines by Peroxynitrite in the Rod and Head Domains of Neurofilament-L

5. Nitric oxide, oxidants, and protein tyrosine nitration

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