Investigating the Role of T7 and T12 Residues on the Biological Properties of Thrombin-Binding Aptamer: Enhancement of Anticoagulant Activity by a Single Nucleobase Modification
Author:
Affiliation:
1. Dipartimento di Chimica delle Sostanze Naturali, ‡Dipartimento di Farmacologia Sperimentale,#Dipartimento di Chimica Farmaceutica e Tossicologica, Università degli Studi di Napoli Federico II, Via D. Montesano 49, 80131 Napoli, Italy
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm301414f
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4. Structural identification of the pathway of long-range communication in an allosteric enzyme
5. Thrombin allostery
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