Spirocyclopropyl β-Lactams as Mechanism-Based Inhibitors of Serine β-Lactamases. Synthesis by Rhodium-Catalyzed Cyclopropanation of 6-Diazopenicillanate Sulfone-Reference-Cited by-同舟云学术

Spirocyclopropyl β-Lactams as Mechanism-Based Inhibitors of Serine β-Lactamases. Synthesis by Rhodium-Catalyzed Cyclopropanation of 6-Diazopenicillanate Sulfone

Published:2003-05-23 Issue:13 Volume:46 Page:2569-2571
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Sandanayaka Vincent P.¹,Prashad Amar S.¹,Yang Youjun¹,Williamson R. Thomas¹,Lin Yang I.¹,Mansour Tarek S.¹

Affiliation:

1. Chemical and Screening Sciences and Infectious Diseases, Wyeth Research, 401 North Middletown Road, Pearl River, New York 10965

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm034056q

Reference20 articles.

1. Resistance to β-Lactam Antibiotics: Structure and Mechanism Based Design of β-Lactamase Inhibitors

2. Micetich, R. G.; Salama, S. M.; Maiti, S. N.; Reddy, A. V. N.; Singh, R. β-Lactamases and Their Inhibitors: An Update.Curr. Med Chem. Anti-Infect. Agents2002,1, 193−213.

Cited by 72 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Rapid Access to Chiral Spiro[2.3] Lactams: Stereoselective Hydroborylation and Hydrosilylation and Remote Control of Axial Chirality by Copper-Catalyzed Desymmetrization of Spirocyclopropenes;Organic Letters;2024-02-28

2. Photocatalytic Radical Cascade Dehalogenation/Carbo-cyclization/Sulfonylation Leading to Indole- and Benzofuran-Based Benzylic Sulfones;The Journal of Organic Chemistry;2023-11-29

3. Silver-mediated radical cascade cyclization of N-allylamides with sodium sulfinates to access sulfonated oxazolines;New Journal of Chemistry;2023

4. Photocatalytic Markovnikov-type addition and cyclization of terminal alkynes leading to 4-sulfonyl quinoline-2(1H)-ones;Chemical Communications;2022

5. Photoredox Catalyzed Radical Cascade Aroylation (Sulfonylation)/Cyclization Enables Access to Fused Indolo-pyridones;The Journal of Organic Chemistry;2021-12-06