Mechanism of Inactivation of Inducible Nitric Oxide Synthase by Amidines. Irreversible Enzyme Inactivation without Inactivator Modification-Reference-Cited by-同舟云学术

Mechanism of Inactivation of Inducible Nitric Oxide Synthase by Amidines. Irreversible Enzyme Inactivation without Inactivator Modification

Published:2004-12-30 Issue:3 Volume:127 Page:858-868
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Zhu Yaoqiu¹,Nikolic Dejan¹,Van Breemen Richard B.¹,Silverman Richard B.¹

Affiliation:

1. Contribution from the Department of Chemistry, Department of Biochemistry, Molecular Biology, and Cell Biology, and Drug Discovery Program, Northwestern University, Evanston, Illinois 60208-3113, and Department of Medicinal Chemistry and Pharmacognosy, University of Illinois at Chicago, Chicago, Illinois 60612-7231

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja0445645

Reference49 articles.

1. The arginine-nitric oxide pathway: A target for new drugs

2. Nitric Oxide: A New Paradigm for Second Messengers

3. Characterization of cell selectivity of two novel inhibitors of nitric oxide synthesis

4. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase

Cited by 47 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SARS-CoV-2 Specific Nanobodies Neutralize Different Variants of Concern and Reduce Virus Load in the Brain of h-ACE2 Transgenic Mice;Viruses;2024-01-25

2. S-Ethyl-Isothiocitrullin-Based Dipeptides and 1,2,4-Oxadiazole Pseudo-Dipeptides: Solid Phase Synthesis and Evaluation as NO Synthase Inhibitors;Molecules;2023-06-29

3. Nanobodies against SARS-CoV-2 reduced virus load in the brain of challenged mice and neutralized Wuhan, Delta and Omicron Variants;2023-03-14

4. New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer;European Journal of Medicinal Chemistry;2023-02

5. Modular Synthesis of Enantioenriched α-Chiral Homoallylic Amidines Enabled by Relay Ir/Cu Catalysis;Organic Letters;2022-09-08