Factor Xa Inhibitors:  S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

Author:

Chan Chuen1,Borthwick Alan D.1,Brown David1,Burns-Kurtis Cynthia L.1,Campbell Matthew1,Chaudry Laiq1,Chung Chun-wa1,Convery Máire A.1,Hamblin J. Nicole1,Johnstone Lisa1,Kelly Henry A.1,Kleanthous Savvas1,Patikis Angela1,Patel Champa1,Pateman Anthony J.1,Senger Stefan1,Shah Gita P.1,Toomey John R.1,Watson Nigel S.1,Weston Helen E.1,Whitworth Caroline1,Young Robert J.1,Zhou Ping1

Affiliation:

1. CVU UK Medicinal Chemistry Department, Screening and Compound Profiling UK, Assay Development UK, Computational and Structural Chemistry, CVU UK DMPK Department, GlaxoSmithKline Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom, and Vascular Inflammatory Diseases, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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