Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides-Reference-Cited by-同舟云学术

Factor Xa Inhibitors: S1 Binding Interactions of a Series of N-{(3S)-1-[(1S)-1-Methyl-2-morpholin-4-yl-2-oxoethyl]-2-oxopyrrolidin-3-yl}sulfonamides

Published:2007-03-06 Issue:7 Volume:50 Page:1546-1557
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chan Chuen¹,Borthwick Alan D.¹,Brown David¹,Burns-Kurtis Cynthia L.¹,Campbell Matthew¹,Chaudry Laiq¹,Chung Chun-wa¹,Convery Máire A.¹,Hamblin J. Nicole¹,Johnstone Lisa¹,Kelly Henry A.¹,Kleanthous Savvas¹,Patikis Angela¹,Patel Champa¹,Pateman Anthony J.¹,Senger Stefan¹,Shah Gita P.¹,Toomey John R.¹,Watson Nigel S.¹,Weston Helen E.¹,Whitworth Caroline¹,Young Robert J.¹,Zhou Ping¹

Affiliation:

1. CVU UK Medicinal Chemistry Department, Screening and Compound Profiling UK, Assay Development UK, Computational and Structural Chemistry, CVU UK DMPK Department, GlaxoSmithKline Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, United Kingdom, and Vascular Inflammatory Diseases, GlaxoSmithKline, 709 Swedeland Road, King of Prussia, Pennsylvania 19406

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060870c

Reference61 articles.

1. The coagulation cascade: initiation, maintenance, and regulation

2. Role of the thrombin receptor in development and evidence for a second receptor

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