Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries-Reference-Cited by-同舟云学术

Synthesis and Profiling of a Diverse Collection of Azetidine-Based Scaffolds for the Development of CNS-Focused Lead-like Libraries

Published:2012-08-10 Issue:17 Volume:77 Page:7187-7211
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Lowe Jason T.¹,Lee Maurice D.¹,Akella Lakshmi B.¹,Davoine Emeline¹,Donckele Etienne J.¹,Durak Landon¹,Duvall Jeremy R.¹,Gerard Baudouin¹,Holson Edward B.¹,Joliton Adrien¹,Kesavan Sarathy¹,Lemercier Berenice C.¹,Liu Haibo¹,Marié Jean-Charles¹,Mulrooney Carol A.¹,Muncipinto Giovanni¹,Welzel-O’Shea Morgan¹,Panko Laura M.¹,Rowley Ann¹,Suh Byung-Chul¹,Thomas Meryl¹,Wagner Florence F.¹,Wei Jingqiang¹,Foley Michael A.¹,Marcaurelle Lisa A.¹

Affiliation:

1. Chemical Biology Platform and ‡Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo300974j

Reference82 articles.

1. Synthesis of Natural-Product-Like Molecules with Over Eighty Distinct Scaffolds

2. Exploring New Chemical Space by Stereocontrolled Diversity-Oriented Synthesis

3. Diversity-oriented synthesis: exploring the intersections between chemistry and biology

4. A Planning Strategy for Diversity-Oriented Synthesis

5. Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery

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