An Unexpected Deamination Reaction after Hydrolysis of the Pyrimidine (6-4) Pyrimidone Photoproduct-Reference-Cited by-同舟云学术

An Unexpected Deamination Reaction after Hydrolysis of the Pyrimidine (6-4) Pyrimidone Photoproduct

Published:2014-09-24 Issue:19 Volume:16 Page:5076-5079
ISSN:1523-7060
Container-title:Organic Letters
language:en
Short-container-title:Org. Lett.

Author:

Lin Gengjie¹,Jian Yajun¹,Ouyang Hao²,Li Lei¹³

Affiliation:

1. Department of Chemistry and Chemical Biology, Indiana University-Purdue University Indianapolis (IUPUI), 402 North Blackford Street, Indianapolis, Indiana 46202, United States

2. Preclinical Pharmacology, Johnson & Johnson, 199 Grandview Road, Skillman, New Jersey 08558, United States

3. Department of Biochemistry and Molecular Biology & Department of Dermatology, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

Funder

National Institute of Environmental Health Sciences

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ol502433h

Reference32 articles.

1. NMR Structures of Damaged DNA

2. Crystal structure of a DNA decamer containing a cis-syn thymine dimer

3. The thymine-thymine pyrimidine-pyrimidone(6-4) ultraviolet light photoproduct is highly mutagenic and specifically induces 3' thymine-to-cytosine transitions in Escherichia coli.