Diastereoselective Total Synthesis of Isocarbacyclin from l-Ascorbic Acid
Author:
Affiliation:
1. School of Education, and Department of Bioscience and Biotechnology, School of Engineering, Okayama University, Tsushima, Okayama, Japan 700-8530 seisaito@biotech.okayama-u.ac.jp
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/jo048738c
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1. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation
2. Synthesis of therapeutically useful prostaglandin and prostacyclin analogs
3. (15R)-16-m-Tolyl-17,18,19,20-tetranorisocarbacyclin: A Stable Ligand with High Binding Affinity and Selectivity for a Prostacyclin Receptor in the Central Nervous System
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