A Prochelator Activated by β-Secretase Inhibits Aβ Aggregation and Suppresses Copper-Induced Reactive Oxygen Species Formation
Author:
Affiliation:
1. Department of Chemistry, Duke University, P.O. Box 90346, Durham, North Carolina 27708
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja100943r
Reference20 articles.
1. The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
2. Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease
3. Alzheimer's Disease: Genes, Proteins, and Therapy
4. Copper and Zinc Binding to Amyloid-β: Coordination, Dynamics, Aggregation, Reactivity and Metal-Ion Transfer
5. Secretase inhibitors and modulators for Alzheimer’s disease treatment
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