Conformation Guides Molecular Efficacy in Docking Screens of Activated β-2 Adrenergic G Protein Coupled Receptor-Reference-Cited by-同舟云学术

Conformation Guides Molecular Efficacy in Docking Screens of Activated β-2 Adrenergic G Protein Coupled Receptor

Published:2013-03-21 Issue:5 Volume:8 Page:1018-1026
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Weiss Dahlia R.¹,Ahn SeungKirl,Sassano Maria F.²,Kleist Andrew,Zhu Xiao,Strachan Ryan,Roth Bryan L.²,Lefkowitz Robert J.,Shoichet Brian K.¹

Affiliation:

1. Department of Pharmaceutical Chemistry, University of California San Francisco, San Francisco, California 94158-2550, United States

2. Department of Pharmacology and National Institute of Mental Health Psychoactive Drug Screening Program School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599, United States

Funder

National Institute of General Medical Sciences

National Institutes of Health

Howard Hughes Medical Institute

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb400103f

Reference41 articles.

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3. Structure-Based Discovery of A2A Adenosine Receptor Ligands

4. Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists

5. Crystal Structure-Based Virtual Screening for Fragment-like Ligands of the Human Histamine H1 Receptor

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