Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis-Reference-Cited by-同舟云学术

Roles of Tyrosine 158 and Lysine 165 in the Catalytic Mechanism of InhA, the Enoyl-ACP Reductase from Mycobacterium tuberculosis

Published:1999-09-23 Issue:41 Volume:38 Page:13623-13634
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Parikh Sapan¹,Moynihan Daniel P.¹,Xiao Guoping¹,Tonge Peter J.¹

Affiliation:

1. Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794-3400, and Graduate Program in Biophysics and Graduate Program in Molecular and Cellular Biochemistry, State University of New York at Stony Brook, Stony Brook, New York 11794

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi990529c

Reference72 articles.

1. Crystal Structure of the Mycobacterium tuberculosis Enoyl-ACP Reductase, InhA, in Complex with NAD+ and a C16 Fatty Acyl Substrate

2. Studies on the Mechanism of Action of Isoniazid and Ethionamide in the Chemotherapy of Tuberculosis

3. Kinetics of Inactivation of WT and C243S Mutant of Mycobacterium tuberculosis Enoyl Reductase by Activated Isoniazid

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