Process Development of a Diacyl Glycerolacyltransferase-1 Inhibitor-Reference-Cited by-同舟云学术

Process Development of a Diacyl Glycerolacyltransferase-1 Inhibitor

Published:2010-02-15 Issue:2 Volume:14 Page:417-424
ISSN:1083-6160
Container-title:Organic Process Research & Development
language:en
Short-container-title:Org. Process Res. Dev.

Author:

Ravn Matthew M.¹,Wagaw Seble H.¹,Engstrom Kenneth M.¹,Mei Jianzhang¹,Kotecki Brian¹,Souers Andrew J.¹,Kym Philip R.¹,Judd Andrew S.¹,Zhao Gang¹

Affiliation:

1. Global Pharmaceutical R&D, Process Research & Development, Abbott Laboratories, 1401 Sheridan Road, North Chicago, Illinois 60064, U.S.A., and Global Pharmaceutical R&D, Discovery, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Illinois 60064, U.S.A.

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/op900310v

Reference19 articles.

1. Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis

2. Cloning of DGAT2, a Second Mammalian Diacylglycerol Acyltransferase, and Related Family Members

3. Diacylglycerol acyltransferases: Potential roles as pharmacological targets

4. Antisense and small-molecule modulation of diacylglycerol acyltransferase

5. Validation of Diacyl Glycerolacyltransferase I as a Novel Target for the Treatment of Obesity and Dyslipidemia Using a Potent and Selective Small Molecule Inhibitor

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