Structure of Adduct X, the Last Unknown of the Six Major DNA Adducts of Mitomycin C Formed in EMT6 Mouse Mammary Tumor Cells-Reference-Cited by-同舟云学术

Structure of Adduct X, the Last Unknown of the Six Major DNA Adducts of Mitomycin C Formed in EMT6 Mouse Mammary Tumor Cells

Published:2000-05-16 Issue:6 Volume:13 Page:479-488
ISSN:0893-228X
Container-title:Chemical Research in Toxicology
language:en
Short-container-title:Chem. Res. Toxicol.

Author:

Palom Yolanda¹,Belcourt Michael F.¹,Musser Steven M.¹,Sartorelli Alan C.¹,Rockwell Sara¹,Tomasz Maria¹

Affiliation:

1. Department of Chemistry, Hunter College, City University of New York, New York, New York 10021, Departments of Pharmacology and Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520, and U.S. Food and Drug Administration, 200 C Street, S.W., Washington, D.C. 20204

Publisher

American Chemical Society (ACS)

Subject

Toxicology,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/tx000024j

Reference32 articles.

1. The mitomycin bioreductive antitumor agents: Cross-linking and alkylation of DNA as the molecular basis of their activity

2. Relationships between functionality and genetic toxicology of selected DNA-damaging agents

3. Modeling of the electrophilic activation of mitomycins: chemical evidence for the intermediacy of a mitosene semiquinone as the active electrophile

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