ECM Architecture-Mediated Regulation of β-Cell Differentiation from hESCs via Hippo-Independent YAP Activation
Author:
Affiliation:
1. Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea
2. Department of Mechanical Engineering, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea
Funder
Korean Fund for Regenerative Medicine
Publisher
American Chemical Society (ACS)
Subject
Biomedical Engineering,Biomaterials
Link
https://pubs.acs.org/doi/pdf/10.1021/acsbiomaterials.2c01054
Reference45 articles.
1. Generation of pancreatic β cells for treatment of diabetes: advances and challenges
2. Islet-like organoids derived from human pluripotent stem cells efficiently function in the glucose responsiveness in vitro and in vivo
3. Extracellular matrix: A dynamic microenvironment for stem cell niche
4. In Search of the Pivot Point of Mechanotransduction: Mechanosensing of Stem Cells
5. Compliant substratum guides endothelial commitment from human pluripotent stem cells
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