Decellularized Brain Extracellular Matrix Hydrogel Aids the Formation of Human Spinal-Cord Organoids Recapitulating the Complex Three-Dimensional Organization

Author:

Wu Weidong123,Liu Youjun23,Liu Renfeng23,Wang Yuhao23,Zhao Yuqi23,Li Hui23,Lu Botao23,Ju Cheng23,Gao Xinlin23,Xu Hailiang23,Cao Yulin45,Cheng Shixiang45,Wang Zhiyuan23,Jia Shuaijun23ORCID,Hu Chunping23,Zhu Lei23,Hao Dingjun123ORCID

Affiliation:

1. Department of Orthopedics, The First Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710061, China

2. Department of Spine Surgery, Honghui Hospital, Xi’an Jiaotong University, Youyi East Road No. 555, Beilin District, Xi’an, Shaanxi, China 710001

3. Shaanxi Key Laboratory of Spine Bionic Treatment, Youyi East Road No. 555, Beilin District, Xi’an, Shaanxi, China 710001

4. Healthina Academy of Cellular Intelligence Manufacturing & Neurotrauma Repair of Tianjin Economic-Technological Development Area, No. 220 DongTing Road, TEDA District, Tianjin 300457, China

5. TANGYI Biomedicine (Tianjin) Co., Ltd. (TBMed), No. 286 Anshan West Road, Nankai District, Tianjin 300190, China

Funder

China Postdoctoral Science Foundation

Tianjin Municipal Science and Technology Program

National Natural Science Foundation of China

Natural Science Foundation of Shaanxi Province

Program of LeLing Health Project of China Aging Development Foundation

Xi'an Municipal Commission of Health

Xi'an scientific research project

Publisher

American Chemical Society (ACS)

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