Prolonged Codelivery of Hemagglutinin and a TLR7/8 Agonist in a Supramolecular Polymer–Nanoparticle Hydrogel Enhances Potency and Breadth of Influenza Vaccination

Author:

Roth Gillie A.1ORCID,Saouaf Olivia M.2,Smith Anton A. A.2,Gale Emily C.3ORCID,Hernández Marcela Alcántara45,Idoyaga Juliana4567,Appel Eric A.12678ORCID

Affiliation:

1. Department of Bioengineering, Stanford University, 443 Via Ortega, Stanford, California 94305, United States

2. Department of Materials Science & Engineering, Stanford University, 496 Lomita Mall, Stanford, California 94305, United States

3. Department of Biochemistry, Stanford University School of Medicine, 279 Campus Drive, Stanford, California 94305, United States

4. Department of Microbiology & Immunology, Stanford University School of Medicine, 299 Campus Drive, Stanford, California 94305, United States

5. Program in Immunology, Stanford University School of Medicine, 240 Pasteur Drive, Stanford, California 94305, United States

6. Institute for Immunity, Transplantation & Infection, Stanford University School of Medicine, 240 Pasteur Drive, Stanford, California 94305, United States

7. ChEM-H Institute, Stanford University, 290 Jane Stanford Way, Stanford, California 94305, United States

8. Department of Pediatrics - Endocrinology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, California 94305, United States

Funder

Novo Nordisk Fonden

Bill and Melinda Gates Foundation

American Cancer Society

Publisher

American Chemical Society (ACS)

Subject

Biomedical Engineering,Biomaterials

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