Microfluidic Disc-on-a-Chip Device for Mouse Intervertebral Disc—Pitching a Next-Generation Research Platform To Study Disc Degeneration

Author:

Dai Jun12ORCID,Xing Yuan3,Xiao Li1ORCID,Li Jingyi4,Cao Ruofan5,He Yi3,Fang Huang2,Periasamy Ammasi5,Oberhozler Jose3,Jin Li1,Landers James P.46,Wang Yong3,Li Xudong1ORCID

Affiliation:

1. Department of Orthopaedic Surgery, University of Virginia, 135 Hospital Drive, Charlottesville, Virginia 22908, United States

2. Department of Orthopaedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Avenue Qiaokou District, Wuhan 430030, P.R. China

3. Department of Surgery, University of Virginia, 345 Cripell Drive, Charlottesville, Virginia 22908, United States

4. Department of Chemistry, University of Virginia, 409 McCormick Road, Charlottesville, Virginia 22904, United States

5. W.M. Keck Center for Cellular Imaging, University of Virginia, 90 Geldard Drive, Charlottesville, Virginia 22904, United States

6. Department of Mechanical and Aerospace Engineering, University of Virginia, 122 Engineer’s Way, Charlottesville, Virginia 22904, United States

Funder

University of Virginia

National Institute of Arthritis and Musculoskeletal and Skin Diseases

Commonwealth Health Research Board

Publisher

American Chemical Society (ACS)

Subject

Biomedical Engineering,Biomaterials

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