Structure-Based Design of Tet Repressor To Optimize a New Inducer Specificity-Reference-Cited by-同舟云学术

Structure-Based Design of Tet Repressor To Optimize a New Inducer Specificity

Published:2004-06-29 Issue:29 Volume:43 Page:9512-9518
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Henssler Eva-Maria¹,Scholz Oliver¹,Lochner Susanne¹,Gmeiner Peter¹,Hillen Wolfgang¹

Affiliation:

1. Lehrstuhl für Mikrobiologie, Institut für Mikrobiologie, Biochemie und Genetik, Friedrich-Alexander Universität Erlangen-Nürnberg, Staudtstrasse 5, 91058 Erlangen, Germany, and Lehrstuhl für Pharmazeutische Chemie, Institut für Pharmazie und Lebensmittelchemie, Friedrich-Alexander Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052 Erlangen, Germany

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi049682j

Reference22 articles.

1. Hillen, W., and Berens, C. b. (1994) Mechanisms underlying expression of Tn10 encoded tetracycline resistance,Annu. Rev. Microbiol.48, 345−369.

2. Kisker, C., Hinrichs, W., Tovar, K., Hillen, W., and Saenger, W. b. (1995) The complex formed between Tet repressor and 9518 tetracycline-Mg2+reveals mechanism of antibiotic resistance,J. Mol. Biol.247, 260−280.

3. Lederer, T., Kintrup, M., Takahashi, M., Sum, P. E., Ellestad, G. A., and Hillen, W. b. (1996) Tetracycline analogs affecting binding to Tn10-Encoded Tet repressor trigger the same mechanism of induction,Biochemistry35, 7439−7446.

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