Extreme Entropy–Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease-Reference-Cited by-同舟云学术

Extreme Entropy–Enthalpy Compensation in a Drug-Resistant Variant of HIV-1 Protease

Published:2012-07-02 Issue:9 Volume:7 Page:1536-1546
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

King Nancy M.¹,Prabu-Jeyabalan Moses¹,Bandaranayake Rajintha M.¹,Nalam Madhavi N. L.¹,Nalivaika Ellen A.¹,Özen Ayşegül¹,Haliloǧlu Türkan²,Yılmaz Neşe Kurt¹,Schiffer Celia A.¹

Affiliation:

1. Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605, United States

2. Polymer Research Center and Department of Chemical Engineering, Bogazici University, TR-34342, Bebek, Istanbul, Turkey

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb300191k

Reference53 articles.

1. STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASE

2. Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant

3. Thermodynamic dissection of the binding energetics of KNI‐272, a potent HIV‐1 protease inhibitor

4. HIV-1 Protease Inhibitors: Enthalpic versus Entropic Optimization of the Binding Affinity

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