Engineering a Ligase Binding DNA Aptamer into a Templating DNA Scaffold to Guide the Selective Synthesis of Circular DNAzymes and DNA Aptamers

Author:

Yan Yu1,Chang Dingran2ORCID,Xu Yongbin3ORCID,Chang Yangyang1,Zhang Qiang4,Yuan Quan5ORCID,Salena Bruno J.6,Li Yingfu2ORCID,Liu Meng1ORCID

Affiliation:

1. School of Environmental Science and Technology, Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), Dalian POCT Laboratory, Dalian University of Technology, Dalian, Liaoning 116024, China

2. Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S4K1, Canada

3. Department of Bioengineering, College of Life Science, Dalian Nationalities University, Dalian, Liaoning 116600, China

4. School of Bioengineering, Dalian University of Technology, Dalian, Liaoning 116024, China

5. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Institute of Chemical Biology and Nanomedicine, Hunan University, Changsha 410082, China

6. Department of Medicine, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S4K1, Canada

Funder

Central University Basic Research Fund of China

Natural Sciences and Engineering Research Council of Canada

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

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