Diastereodivergent Desymmetric Annulation to Access Spirooxindoles: Chemical Probes for Mitosis

Author:

Wen Yu-Hua1,Yang Fengrui2,Li Shuai1,Yao Xuebiao2,Song Jin3ORCID,Gong Liu-Zhu14ORCID

Affiliation:

1. Hefei National Laboratory for Physical Sciences at the Microscale and Department of Chemistry, University of Science and Technology of China, Hefei 230026, China

2. MOE Key Laboratory for Cellular Dynamics and Hefei National Center for Physical Sciences at the Microscale, University of Science and Technology of China, Hefei 230026, China

3. Institutes of Physical Science and Information Technology, Key Laboratory of Environment-Friendly Polymeric Materials of Anhui Province, Anhui University, Hefei 230601, China

4. Center for Excellence in Molecular Synthesis of Chinese Academy of Sciences, Hefei 230026, China

Funder

National Natural Science Foundation of China

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference70 articles.

1. Spirooxindoles: Promising scaffolds for anticancer agents

2. Therapeutic Potential of Spirooxindoles as Antiviral Agents

3. Two New Types of Bisindole Alkaloid from Trigonostemon lutescens

4. Padiya, K.; Kamlesh, J.; Nair, P. S.; Rivindra, R. R.; Chaure, G. S.; Gudade, G. B.; Parkale, S. S.; Manojkumar, V. L.; Swapnil, R. B.; Smita, A. B. Spirocyclic Compounds as voltage-gated sodium channel modulators. World Patent WO2012/49555, 2012.

5. Biological significance of the enantiomeric purity of drugs

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