Ionizable Lipid Nanoparticles for <i>In Vivo</i> mRNA Delivery to the Placenta during Pregnancy-Reference-Cited by-同舟云学术

Ionizable Lipid Nanoparticles for In Vivo mRNA Delivery to the Placenta during Pregnancy

Published:2023-02-15 Issue:8 Volume:145 Page:4691-4706
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Swingle Kelsey L.¹^ORCID,Safford Hannah C.¹,Geisler Hannah C.¹,Hamilton Alex G.¹,Thatte Ajay S.¹,Billingsley Margaret M.¹^ORCID,Joseph Ryann A.¹^ORCID,Mrksich Kaitlin¹,Padilla Marshall S.¹,Ghalsasi Aditi A.¹,Alameh Mohamad-Gabriel²³^ORCID,Weissman Drew²³^ORCID,Mitchell Michael J.¹⁴⁵⁶⁷^ORCID

Affiliation:

1. Department of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

2. Department of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

3. Penn Institute for RNA Innovation, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

4. Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

5. Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

6. Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

7. Institute for Regenerative Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States

Funder

National Center for Advancing Translational Sciences

National Cancer Institute

National Institute of Diabetes and Digestive and Kidney Diseases

National Institute of Dental and Craniofacial Research

Division of Chemical, Bioengineering, Environmental, and Transport Systems

Burroughs Wellcome Fund

National Science Foundation

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c12893

Reference71 articles.

1. Materials for non-viral intracellular delivery of messenger RNA therapeutics

2. Lipid Nanoparticle-Mediated Delivery of mRNA Therapeutics and Vaccines

3. Virus-mediated gene delivery for human gene therapy

4. Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients

5. Non-viral vectors for gene-based therapy

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