Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein–Protein Interaction as a Molecular Glue Drug Discovery Approach-Reference-Cited by-同舟云学术

Reversible Dual-Covalent Molecular Locking of the 14-3-3/ERRγ Protein–Protein Interaction as a Molecular Glue Drug Discovery Approach

Published:2023-03-16 Issue:12 Volume:145 Page:6741-6752
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Somsen Bente A.¹,Schellekens Rick J.C.¹,Verhoef Carlo J.A.¹^ORCID,Arkin Michelle R.²^ORCID,Ottmann Christian¹^ORCID,Cossar Peter J.¹^ORCID,Brunsveld Luc¹^ORCID

Affiliation:

1. Laboratory of Chemical Biology, Department of Biomedical Engineering, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600 MB Eindhoven, The Netherlands

2. Department of Pharmaceutical Chemistry and Small Molecule Discovery Centre (SMDC), University of California, San Francisco, California 94143, United States

Funder

H2020 Marie Sklodowska-Curie Actions

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.2c12781

Reference55 articles.

1. Chemoproteomic methods for covalent drug discovery

2. Contemporary approaches to site-selective protein modification