Structure-Based Design, Synthesis, and Biological Evaluation of Irreversible Human Rhinovirus 3C Protease Inhibitors. 8. Pharmacological Optimization of Orally Bioavailable 2-Pyridone-Containing Peptidomimetics
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Published:2003-09-17
Issue:21
Volume:46
Page:4572-4585
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ISSN:0022-2623
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Container-title:Journal of Medicinal Chemistry
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language:en
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Short-container-title:J. Med. Chem.
Author:
Dragovich Peter S.1, Prins Thomas J.1, Zhou Ru1, Johnson Theodore O.1, Hua Ye1, Luu Hiep T.1, Sakata Sylvie K.1, Brown Edward L.1, Maldonado Fausto C.1, Tuntland Tove1, Lee Caroline A.1, Fuhrman Shella A.1, Zalman Leora S.1, Patick Amy K.1, Matthews David A.1, Wu Ellen Y.1, Guo Ming1, Borer Bennett C.1, Nayyar Naresh K.1, Moran Terence1, Chen Lijian1, Rejto Paul A.1, Rose Peter W.1, Guzman Mark C.1, Dovalsantos Elena Z.1, Lee Steven1, McGee Kevin1, Mohajeri Michael1, Liese Andreas1, Tao Junhua1, Kosa Maha B.1, Liu Bo1, Batugo Minerva R.1, Gleeson Jean-Paul R.1, Wu Zhen Ping1, Liu Jia1, Meador James W.1, Ferre Rose Ann1
Affiliation:
1. Pfizer Global Research and Development-La Jolla, 10777 Science Center Drive, San Diego, California 92121-1111
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Reference50 articles.
1. (a) Couch, R. B. Rhinoviruses. InFieldsVirology,4th ed.; Knipe, D. M., Howley, P. M., et al., Eds.; Lippincott, Williams, & Wilkins Publishers: Philadelphia, 2001; Vol. 1, Chapter 25, pp 777−797. 2. TREATMENT OF THE PICORNA VIRUS COMMON COLD BY INHIBITORS OF VIRAL UNCOATING AND ATTACHMENT 3. RHINOVIRUS COLDS
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