Exploiting the Reaction Flexibility of a Type III Polyketide Synthase through in Vitro Pathway Manipulation
Author:
Affiliation:
1. Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, New York 12180, Life Sciences Institute, Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan 48109
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja0441559
Reference14 articles.
1. Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms
2. The polyketide synthase gene pks4 from Gibberella fujikuroi encodes a key enzyme in the biosynthesis of the red pigment bikaverin
3. Production of a polyketide natural product in nonpolyketide-producing prokaryotic and eukaryotic hosts
4. Modular enzymes
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