Resolution of Chiral Phosphate, Phosphonate, and Phosphinate Esters by an Enantioselective Enzyme Library

Author:

Nowlan Charity1,Li Yingchun1,Hermann Johannes C.1,Evans Timothy1,Carpenter Joseph1,Ghanem Eman1,Shoichet Brian K.1,Raushel Frank M.1

Affiliation:

1. Contribution from the Department of Chemistry, P.O. Box 30012, Texas A&M University, College Station, Texas 77842-3012, and Department of Pharmaceutical Chemistry, University of California, San Francisco, MC 2550, 1700 4th Street, San Francisco, California 94158-2230

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference32 articles.

1. Esaki, N.; Kurihara, T.; Soda, K. InEnzyme Catalysis in OrganicSynthesis; Drauz, K., Waldmann, H., Eds.; Wiley-VCH: Weinheim, Germany, 2002; Vol. III, pp 1281−1332.

2. Syldatk, C.; Muller, R.; Siemann, M.; Wagner, F. InBiocatalyticProduction of Amino Acids and Derivatives; Rozzell, D., Wagner, F., Eds.; Hanser Publishers: Munchen, Germany, 1992; pp 75−128.

3. Mechanism for the Hydrolysis of Organophosphates by the Bacterial Phosphotriesterase

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