Discovery and Evaluation of N-Cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a Selective and Orally Efficacious Inhibitor of Vascular Endothelial Growth Factor Receptor-2-Reference-Cited by-同舟云学术

Discovery and Evaluation of N-Cyclopropyl- 2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5- ylmethyl)amino)benzamide (BMS-605541), a Selective and Orally Efficacious Inhibitor of Vascular Endothelial Growth Factor Receptor-2

Published:2006-05-26 Issue:13 Volume:49 Page:3766-3769
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Borzilleri Robert M.¹,Bhide Rajeev S.¹,Barrish Joel C.¹,D'Arienzo Celia J.¹,Derbin George M.¹,Fargnoli Joseph¹,Hunt John T.¹,Jeyaseelan Robert¹,Kamath Amrita¹,Kukral Daniel W.¹,Marathe Punit¹,Mortillo Steve¹,Qian Ligang¹,Tokarski John S.¹,Wautlet Barri S.¹,Zheng Xiaoping¹,Lombardo Louis J.¹

Affiliation:

1. Bristol-Myers Squibb Pharmaceutical Research Institute, P.O. Box 4000, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm060347y

Reference24 articles.

1. Angiogenesis in cancer, vascular, rheumatoid and other disease

2. Angiogenesis in cancer and other diseases

3. VEGF: an update on biological and therapeutic aspects

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