Biological Evaluation of Bishydroxymethyl-Substituted Cage Dimeric 1,4-Dihydropyridines as a Novel Class of P-Glycoprotein Modulating Agents in Cancer Cells-Reference-Cited by-同舟云学术

Biological Evaluation of Bishydroxymethyl-Substituted Cage Dimeric 1,4-Dihydropyridines as a Novel Class of P-Glycoprotein Modulating Agents in Cancer Cells

Published:2006-04-07 Issue:9 Volume:49 Page:2838-2840
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Richter Martin¹,Molnár Jósef¹,Hilgeroth Andreas¹

Affiliation:

1. Institute of Pharmaceutical Chemistry, Martin-Luther-University Halle-Wittenberg, Wolfgang-Langenbeck-Str. 4, 06120 Halle, Germany, and University of Szeged, Faculty of Medicine, Department of Medical Microbiology, Dóm tér 10, 6720 Szeged, Hungary

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm058046w

Reference13 articles.

1. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal

2. MDR1 gene overexpression confers resistance to imatinib mesylate in leukemia cell line models

3. Reduced effect of gemtuzumab ozogamicin (CMA-676) on P-glycoprotein and/or CD34-positive leukemia cells and its restoration by multidrug resistance modifiers

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