Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction-Reference-Cited by-同舟云学术

Synthesis of Rigidified eIF4E/eIF4G Inhibitor-1 (4EGI-1) Mimetic and Their in Vitro Characterization as Inhibitors of Protein–Protein Interaction

Published:2014-06-04 Issue:12 Volume:57 Page:5094-5111
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mahalingam Poornachandran¹,Takrouri Khuloud¹²,Chen Ting¹²,Sahoo Rupam¹²,Papadopoulos Evangelos³,Chen Limo¹,Wagner Gerhard³,Aktas Bertal H.¹²,Halperin Jose A.¹²,Chorev Michael¹²

Affiliation:

1. Laboratory for Translational Research, Harvard Medical School, One Kendall Square, Cambridge, Massachusetts 02139, United States

2. Hematology Laboratory for Translational Research, Brigham and Women’s Hospital, 20 Shattuck Street, Thorn 7, Boston, Massachusetts 02115, United States

3. Department of Biochemistry and Molecular Pharmacology, Harvard Medical School, 240 Longwood Avenue, Boston, Massachusetts 02115, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401733v

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1. Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

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