Scaffold-Hopping Strategy: Synthesis and Biological Evaluation of 5,6-Fused Bicyclic Heteroaromatics To Identify Orally Bioavailable Anticancer Agents-Reference-Cited by-同舟云学术

Scaffold-Hopping Strategy: Synthesis and Biological Evaluation of 5,6-Fused Bicyclic Heteroaromatics To Identify Orally Bioavailable Anticancer Agents

Published:2011-03-24 Issue:8 Volume:54 Page:3076-3080
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Tung Yen-Shih¹²,Coumar Mohane Selvaraj³,Wu Yu-Shan⁴,Shiao Hui-Yi¹,Chang Jang-Yang⁵,Liou Jing-Ping⁶,Shukla Paritosh¹,Chang Chun-Wei¹,Chang Chi-Yen⁵,Kuo Ching-Chuan⁵,Yeh Teng-Kuang¹,Lin Chin-Yu¹,Wu Jian-Sung¹,Wu Su-Ying¹,Liao Chun-Chen²⁷,Hsieh Hsing-Pang¹

Affiliation:

1. Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, 35 Keyan Road, Zhunan, Miaoli County 350, Taiwan, ROC

2. Department of Chemistry, National Tsing Hua University, 101, Section 2, Guangfu Road, Hsinchu 300, Taiwan, ROC

3. Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Kalapet, Puducherry 605014, India

4. Department of Chemistry, Tunghai University, 181 Taichung Harbor Road Section 3, Taichung 407, Taiwan, ROC

5. National Institute of Cancer Research, National Health Research Institutes, Tainan 704, Taiwan, ROC.

6. College of Pharmacy, Taipei Medical University, Taipei 110, Taiwan, ROC

7. Department of Chemistry, Chung Yuan Christian University, Chungli 320, Taiwan, ROC

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm101027s

Reference14 articles.

1. Molecular Variations Based on Isosteric Replacements

2. Concise Synthesis and Structure−Activity Relationships of Combretastatin A-4 Analogues, 1-Aroylindoles and 3-Aroylindoles, as Novel Classes of Potent Antitubulin Agents

3. Potent Inhibitors of Secretory Phospholipase A2: Synthesis and Inhibitory Activities of Indolizine and Indene Derivatives

4. Preparation and antioxidant activity of α-pyridoin and its derivatives

5. New Practical Synthesis of Indazoles via Condensation of o-Fluorobenzaldehydes and Their O-Methyloximes with Hydrazine

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