β-Amyloid and Neprilysin Computational Studies Identify Critical Residues Implicated in Binding Specificity-Reference-Cited by-同舟云学术

β-Amyloid and Neprilysin Computational Studies Identify Critical Residues Implicated in Binding Specificity

Published:2014-03-31 Issue:4 Volume:54 Page:1157-1165
ISSN:1549-9596
Container-title:Journal of Chemical Information and Modeling
language:en
Short-container-title:J. Chem. Inf. Model.

Author:

Pope Darrick¹,Madura Jeffry D.¹,Cascio Michael¹

Affiliation:

1. Department of Chemistry and Biochemistry and Center for Computational Sciences, Duquesne University, 600 Forbes Avenue, 331 Mellon Hall, Pittsburgh, Pennsylvania 15282, United States

Funder

Pennsylvania Department of Health

Publisher

American Chemical Society (ACS)

Subject

Library and Information Sciences,Computer Science Applications,General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ci500015m

Reference75 articles.

1. The neprilysin (NEP) family of zinc metalloendopeptidases: Genomics and function

2. Mammalian membrane metallopeptidases: NEP, ECE, KELL, and PEX

3. Changes with Age in the Activities of β-Secretase and the Aβ-Degrading Enzymes Neprilysin, Insulin-Degrading Enzyme and Angiotensin-Converting Enzyme

4. Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer’s brain

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