NMR-Based Discovery of Lead Inhibitors That Block DNA Binding of the Human Papillomavirus E2 Protein-Reference-Cited by-同舟云学术

NMR-Based Discovery of Lead Inhibitors That Block DNA Binding of the Human Papillomavirus E2 Protein

Published:1997-09-01 Issue:20 Volume:40 Page:3144-3150
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hajduk Philip J.¹,Dinges Jürgen¹,Miknis Gregory F.¹,Merlock Megan¹,Middleton Tim¹,Kempf Dale J.¹,Egan David A.¹,Walter Karl A.¹,Robins Terry S.¹,Shuker Suzy B.¹,Holzman Thomas F.¹,Fesik Stephen W.¹

Affiliation:

1. Pharmaceutical Products Division, Abbott Laboratories, Abbott Park, Illinois 60064-3500

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm9703404

Reference27 articles.

1. Amino acids necessary for DNA contact and dimerization imply novel motifs in the papillomavirus E2 trans-activator.

2. Trans-activation of an upstream early gene promoter of bovine papilloma virus-1 by a product of the viral E2 gene.

Cited by 160 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Discovery of small molecule entry inhibitors targeting the linoleic acid binding pocket of SARS-CoV-2 spike protein;Journal of Biomolecular Structure and Dynamics;2024-03-23

2. Small Molecule Inhibitors of Human Papillomavirus: A Review of Research from 1997 to 2021;Current Medicinal Chemistry;2023-07-13

3. Fragment-based Ligand Discovery (FBLD);The Handbook of Medicinal Chemistry;2023-02-03

4. Forces Driving a Magic Bullet to Its Target: Revisiting the Role of Thermodynamics in Drug Design, Development, and Optimization;Life;2022-09-15

5. HPV-induced cancers: preclinical therapeutic advancements;Expert Opinion on Investigational Drugs;2022-01-20