Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen-Reference-Cited by-同舟云学术

Design, Synthesis, and Proposed Active Site Binding Analysis of Monocyclic 2-Azetidinone Inhibitors of Prostate Specific Antigen

Published:2001-04-03 Issue:10 Volume:44 Page:1491-1508
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Adlington Robert M.¹,Baldwin Jack E.¹,Becker Gerald W.¹,Chen Beining¹,Cheng Leifeng¹,Cooper Stephen L.¹,Hermann Robert B.¹,Howe Trevor J.¹,McCoull William¹,McNulty Ann M.¹,Neubauer Blake L.¹,Pritchard Gareth J.¹

Affiliation:

1. The Dyson Perrins Laboratory, University of Oxford, South Parks Road, Oxford OX1 3QY, U.K., Eli Lilly and Company, Lilly Research Centre Ltd., Erl Wood Manor, Sunninghill Road, Windlesham, Surrey GU20 6PH, U.K., and Lilly Research Laboratories, Lilly Corporate Center, Indianapolis, Indiana 46285

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000145g

Reference51 articles.

1. Structure and function of prostatic- and seminal vesicle-secreted proteins involved in the gelation and liquefaction of human semen

2. Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease

3. Prostate-Specific Antigen as a Serum Marker for Adenocarcinoma of the Prostate

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