Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases-Reference-Cited by-同舟云学术

Structural Analysis of Isoform-Specific Inhibitors Targeting the Tetrahydrobiopterin Binding Site of Human Nitric Oxide Synthases

Published:2005-06-25 Issue:15 Volume:48 Page:4783-4792
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Matter Hans¹,Kumar H. S. Arun¹,Fedorov Roman¹,Frey Armin¹,Kotsonis Peter¹,Hartmann Elisabeth¹,Fröhlich Lothar G.¹,Reif Andreas¹,Pfleiderer Wolfgang¹,Scheurer Peter¹,Ghosh Dipak K.¹,Schlichting Ilme¹,Schmidt Harald H. H. W.¹

Affiliation:

1. Sanofi-Aventis, Chemical Sciences, Drug Design, Building G 878, D-65926 Frankfurt am Main, Germany, Max Planck Institut für Molekulare Physiologie, Abt. Biophysikalische Chemie, Otto-Hahn-Strasse 11, D-44227 Dortmund, Germany, Institut für Pharmakologie und Toxikologie, Bayerische Julius-Maximilians-Universität Würzburg, Versbacher Strasse 9, D-97078 Würzburg, Germany, Fakultät für Chemie, Universität Konstanz, D-78434 Konstanz, Germany, Vasopharm BIOTECH GmbH, Winchester Strasse 2, D-35398 Giessen,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm050007x

Reference55 articles.

1. Nitric oxide synthases: structure, function and inhibition

2. The Structure of Nitric Oxide Synthase Oxygenase Domain and Inhibitor Complexes

3. Structure of Nitric Oxide Synthase Oxygenase Dimer with Pterin and Substrate

4. Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase

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