Synthesis and Structure−Activity Relationships of Pyrazine-Pyridine Biheteroaryls as Novel, Potent, and Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors-Reference-Cited by-同舟云学术

Synthesis and Structure−Activity Relationships of Pyrazine-Pyridine Biheteroaryls as Novel, Potent, and Selective Vascular Endothelial Growth Factor Receptor-2 Inhibitors

Published:2005-06-24 Issue:15 Volume:48 Page:4892-4909
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kuo Gee-Hong¹,Prouty Catherine¹,Wang Aihua¹,Emanuel Stuart¹,DeAngelis Alan¹,Zhang Yan¹,Song Fengbin¹,Beall Lawrence¹,Connolly Peter J.¹,Karnachi Prahba¹,Chen Xin¹,Gruninger Robert H.¹,Sechler Jan¹,Fuentes-Pesquera Angel¹,Middleton Steven A.¹,Jolliffe Linda¹,Murray William V.¹

Affiliation:

1. Drug Discovery Division, Johnson & Johnson Pharmaceutical Research and Development, L.L.C., 1000 Route 202, P.O. Box 300, Raritan, New Jersey 08869

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm058205b

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5. New concepts in pathogenesis and treatment of diabetic retinopathy

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