1. Division of Physical Chemistry 1, Lund University, P.O. Box 124, 221 00 Lund, Sweden, Department of Physical Chemistry, Chalmers University of Technology, 412 96 Gothenburg, Sweden, Department of Pharmacy, BMC, Uppsala University, P.O. Box 580, 751 23 Uppsala, Sweden, and AstraZeneca R&D Lund, 221 87 Lund, Sweden